HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-[5-(2,3-dimethylphenyl)pyridin-3-yl]benzamide → N-[5-(2,3-dimethylphenyl)piperidin-3-yl]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-[5-(2,3-dimethylphenyl)pyridin-3-yl]benzamide | HCID 66701372 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-[5-(2,3-dimethylphenyl)piperidin-3-yl]benzamide | HCID 66701376 | — |
Reaction Steps
A solution of 550 mg (1.82 mmol) of N-[5-(2,3-dimethylphenyl)pyridin-3-yl]benzamide in 150 ml of ethanol was reacted according to General Method 5A. The solution was concentrated under reduced pressure. The product was purified by preparative HPLC (Reprosil C18, water/acetonitrile gradient). Yield: 760 mg (77% of theory, purity 57%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987248B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-6919c32687a54621a58885854184742a |
| Source note | uspto-grants-2015_03 |