HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aniline → 5-(4-Ethylphenyl)-N-phenyl-1-(pyrrolidin-1-ylcarbonyl)piperidine-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | 5-(4-Ethylphenyl)-1-(pyrrolidin-1-ylcarbonyl)piperidine-3-carboxylic acid | HCID 58002207 | — |
| Product | 5-(4-Ethylphenyl)-N-phenyl-1-(pyrrolidin-1-ylcarbonyl)piperidine-3-carboxamide | HCID 66761263 | — |
Reaction Steps
33 mg (0.10 mmol) of 5-(4-ethylphenyl)-1-(pyrrolidin-1-ylcarbonyl)piperidine-3-carboxylic acid (Example 11A) and 10 mg (0.11 mmol, 1.1 eq.) of aniline were reacted according to General Method 1. Yield: 26 mg (64% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987248B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-3962b0f5f3504fa9b51000bd7326d84f |
| Source note | uspto-grants-2015_03 |