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HRID876290

反应详情

EQUATION

反应方程式

HRID 876290 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1cncc(Cl)c1
HCID247986

5-Chloronicotinic acid

C6H4ClNO2

结构：CCc1ccc(C2CC(N)CN(C(=O)C3CCCC3)C2)cc1.O=C(O)C(F)(F)F
HCID66701344

未命名化合物

PRODUCTS

生成物

1
结构：CCc1ccc(C2CC(NC(=O)c3cncc(Cl)c3)CN(C(=O)C3CCCC3)C2)cc1
HCID46931745

未命名化合物

PROCEDURE

实验过程

65 mg (0.15 mmol) of 1-(cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-amine trifluoroacetate (Example 8A) and 21 mg (0.13 mmol, 0.9 eq.) of 5-chloropyridine-3-carboxylic acid were reacted according to General Method 1. Yield: 39 mg (62% of theory)