huagongshe.com
HRID876291

反应详情

EQUATION

反应方程式

HRID 876291 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1ccc(Br)cn1
HCID608544

5-bromopyridine-2-carboxylic acid

C6H4BrNO2

结构：CCc1ccc(C2CC(N)CN(C(=O)C3CCCC3)C2)cc1.O=C(O)C(F)(F)F
HCID66701344

未命名化合物

PRODUCTS

生成物

1
结构：CCc1ccc(C2CC(NC(=O)c3ccc(Br)cn3)CN(C(=O)C3CCCC3)C2)cc1
HCID66761509

未命名化合物

PROCEDURE

实验过程

139 mg (0.34 mmol) of 1-(cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-amine trifluoroacetate (Example 8A) and 68 mg (0.34 mmol, 1.0 eq.) of 5-bromopyridine-2-carboxylic acid were reacted according to General Method 1. Yield: 75 mg (44% of theory)