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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 876291생성일: 2026년 10월 25일

5-Bromopyridine-2-carboxylic acid → 5-Bromo-N-[1-(cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidin-3-yl]pyridine-2-carboxamide

https://huagongshe.com/reaction/876291

반응식

참여 물질

역할이름HCID투입량
반응물5-Bromopyridine-2-carboxylic acidHCID 608544—
반응물1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-amine trifluoroacetateHCID 66701344—
생성물5-Bromo-N-[1-(cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidin-3-yl]pyridine-2-carboxamideHCID 66761509—

반응 단계

139 mg (0.34 mmol) of 1-(cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-amine trifluoroacetate (Example 8A) and 68 mg (0.34 mmol, 1.0 eq.) of 5-bromopyridine-2-carboxylic acid were reacted according to General Method 1. Yield: 75 mg (44% of theory)

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08987248B2
출처 데이터셋uspto-grants-2015_03
ORD IDord-18accb3768bb478392ef44bd3b7fec4b
출처 메모uspto-grants-2015_03