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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 876303Generated: October 30, 2026

Isocyanatocyclopropane → HCID 66761748, compound

https://huagongshe.com/reaction/876303

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsocyanatocyclopropaneHCID 637659—
Reactant1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-amine trifluoroacetateHCID 66701344—
ProductHCID 66761748HCID 66761748—

Reaction Steps

108 mg (0.22 mmol) of 1-(cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-amine trifluoroacetate (Example 7A) and 22 mg (0.26 mmol, 1.2 eq.) of cyclopropyl isocyanate were reacted according to General Method 4. Yield: 64 mg (76% of theory)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987248B2
Source datasetuspto-grants-2015_03
ORD IDord-9c1e5209869f4ab1ba71687603eedf59
Source noteuspto-grants-2015_03