反应详情

To the product from Step A (0.032 g, 0.0601 mmol) was added CHCl3 (0.600 mL) and HCl (0.451 mL, 1.80 mmol, 4.0M in dioxane). The mixture was stirred at ambient temperature for 9 hours, then diluted with Et2O (5 mL) and filtered. The solid was washed with Et2O and dried in vacuo. This provided 0.026 g (82%) of the desired product as a pale yellow solid. MS ESI (+) m/z 433.1 (M+1) detected.

1. filtrationfiltered
2. washThe solid was washed with Et2O
3. customdried in vacuo