HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67222305, compound → HCID 58181897, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67222305 | HCID 67222305 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | MeOH tetrahydrofuran | HCID 21899815 | — |
| Product | HCID 58181897 | HCID 58181897 | 97.8% |
Reaction Steps
To a solution of compound 39-1 (0.3 g) in MeOH-THF (3 mL-3 mL), was added 10% Pd/C (30 mg). The reaction mixture was stirred under hydrogen atmosphere for 3 hours at room temperature. Then the reaction mixture was filtered with Celite® pad to remove catalyst. The filtrate was concentrated in vacuo to obtain compound 39-2 (0.27 g) as pale brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987242B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-1abb17ad1e6b47ab9540db3775b419d7 |
| Source note | uspto-grants-2015_03 |