Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Iodobenzoic acid → HCID 136337793, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Iodobenzoic acid | HCID 12060 | — |
| 반응물 | 4,4-Difluoropiperidine | HCID 2758352 | — |
| 반응물 | HCID 67222792 | HCID 67222792 | — |
| 반응물 | HCID 178507458 | HCID 178507458 | — |
| 생성물 | HCID 136337793 | HCID 136337793 | 58.7% |
반응 단계
According to the Step 77-1 in synthetic method for EXAMPLE 77, compound 116-2 (94 mg) and 3-(4-aminophenyl)-1,2,4-oxadiazol-5(2H)-one (79.2 mg) were used instead of 3-iodobenzoic acid and 4,4-difluoropiperidine to obtain compound 116-3 (83 mg) as a pale yellow amorphous solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08987242B2 |
| 출처 데이터셋 | uspto-grants-2015_03 |
| ORD ID | ord-1c986cbfb749497abde96fc05a446243 |
| 출처 메모 | uspto-grants-2015_03 |