Toluene → 4-[4-(2-fluoro-benzenesulfonyl)-2,2-dimethyl-3,4-dihydro-2H-benzo[1,4]oxazin-8-yl]-piperazine-1-carboxylic acid tert-butyl ester
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:11]1[O:10][C:9]([CH3:12])([CH3:13])[CH2:8][N:7]2[S:14](=[O:15])(=[O:16])[c:17]1[c:18]([F:23])[cH:19][cH:20][cH:21][cH:22]1.[C:24](=[O:25])([O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[N:31]1[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]1.[CH3:83][CH2:84][O:85][C:86](=[O:87])[CH3:88].[CH3:89][c:90]1[cH:91][cH:92][cH:93][cH:94][cH:95]1.[cH:37]1[cH:38][cH:39][c:40]([P:41]([c:42]2[cH:43][cH:44][c:45]3[c:46]([cH:47][cH:48][cH:49][cH:50]3)[c:51]2-[c:52]2[c:53]3[c:54]([cH:55][cH:56][cH:57][cH:58]3)[cH:59][cH:60][c:61]2[P:62]([c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)[c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)[c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)[cH:81][cH:82]1>>[c:2]1([N:34]2[CH2:33][CH2:32][N:31]([C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[CH2:36][CH2:35]2)[cH:3][cH:4][cH:5][c:6]2[c:11]1[O:10][C:9]([CH3:12])([CH3:13])[CH2:8][N:7]2[S:14](=[O:15])(=[O:16])[c:17]1[c:18]([F:23])[cH:19][cH:20][cH:21][cH:22]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-1d723771d9254fbd86446757059ff520
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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