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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 87670Generated: October 30, 2026

1,2-Dichloroethane → 8-fluoro-N-(4-fluorophenyl)-1-(4-(trifluoromethyl)phenyl)-3,4-dihydroisoquinoline-2(1H)-carboxamide

https://huagongshe.com/reaction/87670

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantMethanolHCID 887—
Reactant4-Fluorophenyl isocyanateHCID 70955—
ReactantDiisopropylethylamineHCID 81531—
Reactant8-Fluoro-1-(4-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinolineHCID 57326308—
Product8-fluoro-N-(4-fluorophenyl)-1-(4-(trifluoromethyl)phenyl)-3,4-dihydroisoquinoline-2(1H)-carboxamideHCID 42634732—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-beb31081ce9b4ee3a9855f4194aa9513
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)