1,2-Dichloroethane → 8-fluoro-N-(4-fluorophenyl)-1-(4-(trifluoromethyl)phenyl)-3,4-dihydroisoquinoline-2(1H)-carboxamide
Reaction equation
[CH3:45][OH:46].[CH:22]([N:23]([CH:24]([CH3:25])[CH3:26])[CH2:27][CH3:28])([CH3:29])[CH3:30].[Cl:41][CH2:42][CH2:43][Cl:44].[F:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:11]1[CH:10]([c:12]1[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]1)[NH:9][CH2:8][CH2:7]2.[F:31][c:32]1[cH:33][cH:34][c:35]([N:38]=[C:39]=[O:40])[cH:36][cH:37]1>>[F:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:11]1[CH:10]([c:12]1[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]1)[N:9]([C:39]([NH:38][c:35]1[cH:34][cH:33][c:32]([F:31])[cH:37][cH:36]1)=[O:40])[CH2:8][CH2:7]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-beb31081ce9b4ee3a9855f4194aa9513
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…