HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formic Acid → HCID 178507597, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formic Acid | HCID 284 | — |
| Reactant | Sodium Sulfite | HCID 24437 | — |
| Reactant | 5-chlorothiazolo[5,4-b]pyridin-2-amine | HCID 4266064 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 178507597 | HCID 178507597 | — |
Reaction Steps
5-Chlorothiazolo[5,4-b]pyridin-2-amine (Q-2) (19 g, 103 mmol) containing sodium sulfite (2 g) was refluxed in 20% aqueous sodium hydroxide solution (150 mL) overnight. The solids were completely dissolved after 1 h, then cooled to room temperature. The solution was neutralized with formic acid. A precipitate was collected by filtration as the title compound (16.4 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987269B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-0c0faf03469e4a188507d29fc1fbc16b |
| Source note | uspto-grants-2015_03 |