1-Methylpiperazine → HCID 46261792, compound

HRID 876942Notes

Reaction equation

HRID 876942 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][NH:5][CH2:4][CH2:3]1.Cl[C:9]1[N:14]=[C:13]([Cl:15])[N:12]=[C:11]2[N:16]([CH3:19])[N:17]=[CH:18][C:10]=12>>[Cl:15][C:13]1[N:12]=[C:11]2[N:16]([CH3:19])[N:17]=[CH:18][C:10]2=[C:9]([N:5]2[CH2:6][CH2:7][N:2]([CH3:1])[CH2:3][CH2:4]2)[N:14]=1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 2222474,6-dichloro-1-methyl-1H-pyrazolo(3,4-d)pyrimidine

Product 1

HCID 46261792HCID 46261792, compound

Procedure

Reaction of N-methylpiperazine with 4,6-dichloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine 5 by General Procedure B gave 6-chloro-1-methyl-4-(4-methyl-piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine.

Sources & evidence

ORD record
ord-cc4730c0ff634665bdfb44d5501c2f6d
Source dataset
uspto-grants-2015_03
Patent number
US08987280B2

Reaction notes

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