Phenylboronic Acid → HCID 67312064, compound

HRID 876965Notes

Reaction equation

HRID 876965 reaction equation
Cl[C:2]1[C:3]2[N:11]=[N:10][N:9]([CH2:12][C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([CH2:19][O:20][C@H:21]4[CH2:25][CH2:24][O:23][CH2:22]4)[N:14]=3)[C:4]=2[N:5]=[C:6]([NH2:8])[N:7]=1.[C:26]1(B(O)O)[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[C:26]1([C:2]2[C:3]3[N:11]=[N:10][N:9]([CH2:12][C:13]4[CH:18]=[CH:17][CH:16]=[C:15]([CH2:19][O:20][CH:21]5[CH2:25][CH2:24][O:23][CH2:22]5)[N:14]=4)[C:4]=3[N:5]=[C:6]([NH2:8])[N:7]=2)[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1

Participants

3

Reactant 2

HCID 66827Phenylboronic AcidHCID 86655317HCID 86655317, compound

Product 1

HCID 67312064HCID 67312064, compound

Procedure

This was prepared from 7-chloro-3-{6-[(S)-(tetrahydrofuran-3-yl)oxymethyl]pyridin-2-ylmethyl}-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-ylamine and phenylboronic acid by the method of Example 13 to give 0.060 g (68%).

Workup

  1. customto give 0.060 g (68%)

Sources & evidence

ORD record
ord-5fe3dd86b3e14fff95f4c83215923c40
Source dataset
uspto-grants-2015_03
Patent number
US08987279B2

Reaction notes

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