反应详情

2.65 g of compound 8.1 (10 mmol) was suspended in MeOH (50 ml) and treated wet 5% Pt/C (Degussa type, Aldrich, 1.5 g). The flask is flushed with hydrogen gas from a balloon and the reaction mixture was stirred under hydrogen balloon for 2 hours. The reaction mixture was filtered through a Celite plug and the solvent is removed under reduced pressure to yield 2.0 g of the desired product.

1. customThe flask is flushed with hydrogen gas from a balloon
2. filtrationThe reaction mixture was filtered through a Celite plug
3. customthe solvent is removed under reduced pressure