HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → [4-(Bromomethyl)phenyl](cyclopentyl)acetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | [4-(Bromomethyl)phenyl](cyclopentyl)acetic acid | HCID 21255101 | — |
| Product | [4-(Bromomethyl)phenyl](cyclopentyl)acetyl chloride | HCID 58136560 | — |
Reaction Steps
246 mg (0.766 mmol) of [4-(bromomethyl)phenyl](cyclopentyl)acetic acid were dissolved in 5 ml of thionyl chloride, and the mixture was stirred at room temperature for 1 h and then at 50° C. for 1 h. The mixture was then concentrated under reduced pressure. This gave 253 mg of the title compound, which was reacted without further purification in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987256B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-c19338cd04614188bb48453fc84ac4d3 |
| Source note | uspto-grants-2015_03 |