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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 877180Generated: October 29, 2026

Thionyl Chloride → [4-(Bromomethyl)phenyl](cyclopentyl)acetyl chloride

https://huagongshe.com/reaction/877180

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
Reactant[4-(Bromomethyl)phenyl](cyclopentyl)acetic acidHCID 21255101—
Product[4-(Bromomethyl)phenyl](cyclopentyl)acetyl chlorideHCID 58136560—

Reaction Steps

246 mg (0.766 mmol) of [4-(bromomethyl)phenyl](cyclopentyl)acetic acid were dissolved in 5 ml of thionyl chloride, and the mixture was stirred at room temperature for 1 h and then at 50° C. for 1 h. The mixture was then concentrated under reduced pressure. This gave 253 mg of the title compound, which was reacted without further purification in the next step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987256B2
Source datasetuspto-grants-2015_03
ORD IDord-c19338cd04614188bb48453fc84ac4d3
Source noteuspto-grants-2015_03