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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 877248Generated: October 28, 2026

Trifluoroacetic acid → HCID 58136718, compound

https://huagongshe.com/reaction/877248

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 58136578HCID 58136578—
SolventDichloromethaneHCID 6344—
ProductHCID 58136718HCID 58136718—

Reaction Steps

390 mg (0.90 mmol) of tert-butyl(+/−)-cyclopentyl(4-{[2-oxo-5-(trifluoromethyl)pyridin-1(2H)-yl]methyl}phenyl)ethanoate were initially charged in 2.7 ml of dichloromethane, and 690 μl of trifluoroacetic acid were added. The reaction mixture was stirred at RT for 2 h and then concentrated under reduced pressure, and the residue was dried under high vacuum. This gave 523 mg of product, which was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987256B2
Source datasetuspto-grants-2015_03
ORD IDord-87f337684f5e4391bd34eabd920a57c8
Source noteuspto-grants-2015_03