HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 58136718, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 58136578 | HCID 58136578 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 58136718 | HCID 58136718 | — |
Reaction Steps
390 mg (0.90 mmol) of tert-butyl(+/−)-cyclopentyl(4-{[2-oxo-5-(trifluoromethyl)pyridin-1(2H)-yl]methyl}phenyl)ethanoate were initially charged in 2.7 ml of dichloromethane, and 690 μl of trifluoroacetic acid were added. The reaction mixture was stirred at RT for 2 h and then concentrated under reduced pressure, and the residue was dried under high vacuum. This gave 523 mg of product, which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987256B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-87f337684f5e4391bd34eabd920a57c8 |
| Source note | uspto-grants-2015_03 |