HRID877339

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID69331

4-Aminobenzyl alcohol

C7H9NO

结构：O=C(O)COc1cccc([C@@H](NC(=O)O[C@H]2CN3CCC2CC3)c2ccccc2)c1

HCID90198139

未命名化合物

PRODUCTS

生成物

结构：O=C(COc1cccc([C@@H](NC(=O)O[C@H]2CN3CCC2CC3)c2ccccc2)c1)Nc1ccc(CO)cc1

HCID90204880

未命名化合物

PROCEDURE

实验过程

The title compound was prepared as described in Example 1 Step 10 with 2-(3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)acetic acid replacing 4-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl) phenoxy)methyl)benzoic acid and 4-aminobenzyl alcohol replacing 4-(2-hydroxyethoxy)-3-methylbenzaldehyde.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d8a88082c3b24b1ca1749d2e2448b4bd
来源数据集: uspto-grants-2015_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08987299B2
来源说明: uspto-grants-2015_03

反应 SMILES

[C:1]1([C@H:7]([NH:19][C:20]([O:22][C@@H:23]2[CH:28]3[CH2:29][CH2:30][N:25]([CH2:26][CH2:27]3)[CH2:24]2)=[O:21])[C:8]2[CH:9]=[C:10]([CH:16]=[CH:17][CH:18]=2)[O:11][CH2:12][C:13]([OH:15])=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:31][C:32]1[CH:39]=[CH:38][C:35]([CH2:36][OH:37])=[CH:34][CH:33]=1>>[N:25]12[CH2:26][CH2:27][CH:28]([CH2:29][CH2:30]1)[C@@H:23]([O:22][C:20](=[O:21])[NH:19][C@H:7]([C:8]1[CH:18]=[CH:17][CH:16]=[C:10]([O:11][CH2:12][C:13]([NH:31][C:32]3[CH:39]=[CH:38][C:35]([CH2:36][OH:37])=[CH:34][CH:33]=3)=[O:15])[CH:9]=1)[C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)[CH2:24]2