Piperidine-1-propylamine → HCID 89689694, compound

HRID 877545Notes

Reaction equation

HRID 877545 reaction equation
[Cl:1][C:2]1[N:7]=[CH:6][C:5]([C:8]2[S:9][CH:10]=[C:11]([C:13]([N:15]3[CH2:20][CH2:19][CH2:18]C(O)C3)=[O:14])[N:12]=2)=[C:4]([NH:22][CH:23]([CH3:25])[CH3:24])[CH:3]=1.[NH:26]1[CH2:31][CH2:30][CH2:29][CH:28](O)[CH2:27]1.N1(CCCN)CCCC[CH2:34]1>>[Cl:1][C:2]1[N:7]=[CH:6][C:5]([C:8]2[S:9][C:10]([CH3:34])=[C:11]([C:13]([NH:15][CH2:20][CH2:19][CH2:18][N:26]3[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]3)=[O:14])[N:12]=2)=[C:4]([NH:22][CH:23]([CH3:24])[CH3:25])[CH:3]=1

Participants

4

Reactant 3

HCID 19049Piperidine-1-propylamineHCID 232933-HydroxypiperidineHCID 89689614HCID 89689614, compound

Product 1

HCID 89689694HCID 89689694, compound

Procedure

Followed the same procedure as mentioned in the synthesis of compound no. 24a, instead of piperidin-3-ol, 3-(piperidin-1-yl)propan-1-amine was used.

Workup

  1. customas mentioned in the synthesis of compound no

Sources & evidence

ORD record
ord-60e16197e4b3494dbf19cdf90bd27e47
Source dataset
uspto-grants-2015_03
Patent number
US08987311B2

Reaction notes

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