3-Hydroxypiperidine → HCID 89689750, compound

HRID 877546Notes

Reaction equation

HRID 877546 reaction equation
[Cl:1][C:2]1[N:7]=[CH:6][C:5]([C:8]2[S:9][CH:10]=[C:11]([C:13]([N:15]3CCCC(O)C3)=[O:14])[N:12]=2)=[C:4]([NH:22][CH:23]([CH3:25])[CH3:24])[CH:3]=1.N1CCCC(O)[CH2:27]1.[Cl-].[NH4+]>>[Cl:1][C:2]1[N:7]=[CH:6][C:5]([C:8]2[S:9][C:10]([CH3:27])=[C:11]([C:13]([NH2:15])=[O:14])[N:12]=2)=[C:4]([NH:22][CH:23]([CH3:24])[CH3:25])[CH:3]=1

Participants

4

Reactant 3

HCID 232933-HydroxypiperidineHCID 25517Ammonium ChlorideHCID 89689614HCID 89689614, compound

Product 1

HCID 89689750HCID 89689750, compound

Procedure

Followed the same procedure as mentioned in the synthesis of compound no. 24a, instead of piperidin-3-ol, ammonium chloride was used.

Workup

  1. customas mentioned in the synthesis of compound no

Sources & evidence

ORD record
ord-f525ab4d80f240d6b60fc66043a0550c
Source dataset
uspto-grants-2015_03
Patent number
US08987311B2

Reaction notes

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