反应详情

温度

5 °C

Mixture of ethyl 2-((4R,6S)-6-(acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate (80 grams), potassium carbonate (21 grams) in methanol (400 ml) was stirred for 2 hours at 0-10° C. The reaction mixture was quenched with water and then the reaction mixture extracted into methylene chloride and washed it with water. The methylene chloride from the reaction mixture was distilled off under reduced pressure to get the title compound.

1. customThe reaction mixture was quenched with water
2. extractionthe reaction mixture extracted into methylene chloride
3. washwashed it with water
4. distillationThe methylene chloride from the reaction mixture was distilled off under reduced pressure