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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 877987Generated: October 29, 2026

HCID 70663581, compound → HCID 43114092, compound

https://huagongshe.com/reaction/877987

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 70663581HCID 70663581—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 43114092HCID 4311409236%

Reaction Steps

2-Methyl-3′-nitro-3,4,5,6-tetrahydro-2H-[1,4′]bipyridinyl (650 mg, 2.94 mmol) and 10% palladium on carbon (156 mg, 0.15 mmol) in EtOH were stirred under 1 atmosphere of hydrogen gas for 16 hours. Filtration followed by removal of volatiles under reduced pressure gave the title compound (200 mg, 36%) which was used in the next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987307B2
Source datasetuspto-grants-2015_03
ORD IDord-9e43d6607acb4147aa4263c502ae9202
Source noteuspto-grants-2015_03