HRID878023

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID44754881

(5-Chloro-2-methoxypyridin-3-yl)boronic acid

C6H7BClNO3

结构：CN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnccc1Br

HCID86670692

未命名化合物

PRODUCTS

生成物

结构：COc1ncc(Cl)cc1-c1ccncc1N(C)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1

HCID60196804

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

The title compound was prepared in analogy to example 25, from N-(4-bromo-pyridin-3-yl)-N-methyl-3,5-bis-trifluoromethyl-benzamide (example 25, intermediate a) and 5-chloro-2-methoxypyridine-3-boronic acid (CAS RN 943153-22-8) and using DMF as reaction solvent. Off-white solid (28%). MS (ESI): m/z=490.0 [M+H]+.

WORKUP

后处理

customas reaction solvent