HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-3-fluoro-4-iodopyridine → (2'-Chloro-3'-fluoro-[4,4]bipyridinyl-3-yl)-methyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-3-fluoro-4-iodopyridine | HCID 11065087 | — |
| Reactant | N-Methyl-N-(2-methyl-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-3'-yl)-3,5-bis-trifluoromethyl-benzamide | HCID 86670691 | — |
| Product | (2'-Chloro-3'-fluoro-[4,4]bipyridinyl-3-yl)-methyl-amine | HCID 86670705 | — |
Reaction Steps
The title compound was prepared in analogy to example 55, intermediate, from 2-chloro-3-fluoro-4-iodo-pyridine (CAS RN 148639-07-0) and (4-iodo-pyridin-3-yl)-methyl-amine (example 36, intermediate b). Brown sticky solid (86%). MS (ESI): m/z=238.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987307B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-bc708d68db9740039717f753fd91180e |
| Source note | uspto-grants-2015_03 |