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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 878037Generated: October 30, 2026

N-Methyl-N-(2-methyl-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-3'-yl)-3,5-bis-trifluoromethyl-benzamide → Methyl-(3-methyl-[2,4]bipyridinyl-3'-yl)-amine

https://huagongshe.com/reaction/878037

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-N-(2-methyl-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-3'-yl)-3,5-bis-trifluoromethyl-benzamideHCID 86670691—
ReactantHCID 178426320HCID 178426320—
ProductMethyl-(3-methyl-[2,4]bipyridinyl-3'-yl)-amineHCID 70663197—

Reaction Steps

The title compound was prepared in analogy to example 55, intermediate, from 3-methyl-2-pyridylzinc bromide (CAS RN 308795-91-7) and (4-iodo-pyridin-3-yl)-methyl-amine (example 36, intermediate b). Light yellow sticky solid (93%). MS (ESI): m/z=200.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987307B2
Source datasetuspto-grants-2015_03
ORD IDord-5394ea5d37634eaf91bf7df10ad7f688
Source noteuspto-grants-2015_03