HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methyl-N-(2-methyl-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-3'-yl)-3,5-bis-trifluoromethyl-benzamide → Methyl-(3-methyl-[2,4]bipyridinyl-3'-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methyl-N-(2-methyl-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-3'-yl)-3,5-bis-trifluoromethyl-benzamide | HCID 86670691 | — |
| Reactant | HCID 178426320 | HCID 178426320 | — |
| Product | Methyl-(3-methyl-[2,4]bipyridinyl-3'-yl)-amine | HCID 70663197 | — |
Reaction Steps
The title compound was prepared in analogy to example 55, intermediate, from 3-methyl-2-pyridylzinc bromide (CAS RN 308795-91-7) and (4-iodo-pyridin-3-yl)-methyl-amine (example 36, intermediate b). Light yellow sticky solid (93%). MS (ESI): m/z=200.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987307B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-5394ea5d37634eaf91bf7df10ad7f688 |
| Source note | uspto-grants-2015_03 |