HCID 70663545, compound → HCID 70663169, compound

HRID 878081Notes

Reaction equation

HRID 878081 reaction equation
C(OC(=O)[N:7]([C:12]1[CH:13]=[N:14][CH:15]=[CH:16][C:17]=1[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[Cl:24])[CH2:8][CH2:9][O:10][CH3:11])(C)(C)C>CCCCCCC.CCOC(C)=O>[Cl:24][C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=1[C:17]1[CH:16]=[CH:15][N:14]=[CH:13][C:12]=1[NH:7][CH2:8][CH2:9][O:10][CH3:11]

Participants

3

Reactant 1

HCID 70663545HCID 70663545, compound

Product 1

HCID 70663169HCID 70663169, compound

Reagents, catalysts & solvents 1

HCID 21899848Ethylacetate heptaneSolvent

Procedure

The title compound was prepared in analogy to example 85, intermediate a, from [4-(2-chloro-phenyl)-pyridin-3-yl]-(2-methoxy-ethyl)-carbamic acid tert-butyl ester and using a gradient of n-heptane:EtOAc (100:0 to 0:100) for the chromatographic purification. Colorless oil (72%). MS (ESI): m/z=263.094 [M+H]+.

Workup

  1. customfor the chromatographic purification

Sources & evidence

ORD record
ord-37ad8bc86c3745308257c2e87f43dc08
Source dataset
uspto-grants-2015_03
Patent number
US08987307B2

Reaction notes

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