反应详情

The title compound was prepared in analogy to example 72, from (4-iodo-pyridin-3-ylamino)-acetic acid methyl ester (example 176, intermediate b) and 2-fluorophenylboronic acid (CAS RN 1193-03-9) and using a gradient of n-heptane:EtOAc (100:0 to 0:100) for the chromatographic purification. Off-white solid (37%). MS (ESI): m/z=261.104 [M+H]+.

1. customfor the chromatographic purification