huagongshe.com
HRID878243

反应详情

EQUATION

反应方程式

HRID 878243 的结构方程式

REACTANTS

反应物

3
结构：CI
HCID6328

Methyl iodide

CH3I

结构：CC(C)(C)OC(=O)Nc1c(I)ccnc1Cl
HCID24229170

tert-Butyl (2-chloro-4-iodopyridin-3-yl)carbamate

C10H12ClIN2O2

结构：CS(=O)(=O)CCN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnccc1-c1ccccc1Cl
HCID86670734

未命名化合物

PRODUCTS

生成物

1
结构：CN(C(=O)OC(C)(C)C)c1c(I)ccnc1Cl
HCID86670802

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCCCCCC.CCOC(C)=O
溶剂HCID21899848

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in analogy to example 85, intermediate c, from (2-chloro-4-iodo-pyridin-3-yl)-carbamic acid tert-butyl ester (CAS RN 855784-39-3) and methyl iodide and using a gradient of n-heptane:EtOAc (100:0 to 50:50) for the chromatographic purification. Colorless solid (88%). MS (ESI): m/z=368.99 [M+H]+.

WORKUP

后处理

  1. customfor the chromatographic purification