Diallylamine → HCID 117629641, compound

HRID 878407Notes

Reaction equation

HRID 878407 reaction equation
[O:1]1[CH:6]2[CH:2]1[CH2:3][O:4][CH2:5]2.[CH2:7]([NH:10][CH2:11][CH:12]=[CH2:13])[CH:8]=[CH2:9]>C(O)C>[CH2:7]([N:10]([CH2:11][CH:12]=[CH2:13])[C@@H:6]1[CH2:5][O:4][CH2:3][C@H:2]1[OH:1])[CH:8]=[CH2:9]

Participants

4

Reactant 2

HCID 31279DiallylamineHCID 675113,6-Dioxabicyclo[3.1.0]hexane

Product 1

HCID 117629641HCID 117629641, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
75 °C

Procedure

To a solution of 3,4-epoxytetrahydrofuran (57.4 g, 0.67 mol) in ethanol (344 mL) was added diallylamine (194 g, 2.00 mol). The reaction mixture was heated to 75° C. After 2 days, the reaction mixture was cooled and concentrated under reduced pressure to afford trans-4-(diprop-2-en-1-ylamino)tetrahydrofuran-3-ol. The material was used without further purification.

Workup

  1. temperaturethe reaction mixture was cooled
  2. concentrationconcentrated under reduced pressure

Sources & evidence

ORD record
ord-305b344a04bb4719bb58a8da6463c86a
Source dataset
uspto-grants-2015_03
Patent number
US08987456B2

Reaction notes

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