Ammonia → HCID 131732615, compound

HRID 878435Notes

Reaction equation

HRID 878435 reaction equation
[Cl:1][C:2]1[N:7]=[CH:6][C:5]([NH:8][C@H:9]2[CH:16]3[CH2:17][N:12]4[CH2:13][CH:14]([CH2:18][CH:10]2[CH2:11]4)[CH2:15]3)=[CH:4][CH:3]=1.N>>[ClH:1].[ClH:1].[ClH:1].[Cl:1][C:2]1[N:7]=[CH:6][C:5]([NH:8][C@H:9]2[CH:16]3[CH2:17][N:12]4[CH2:13][CH:14]([CH2:18][CH:10]2[CH2:11]4)[CH2:15]3)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 86621359HCID 86621359, compound

Product 1

HCID 131732615HCID 131732615, compound

Procedure

Prepared from the product of Example 65B (100 mg, 0.38 mmol) according to Method H: 1H NMR (300 MHz, methanol-D4) δ ppm 2.08-2.52 (m, 7H), 3.40-3.61 (m, 4H), 3.75-3.90 (m, 3H), 7.54-7.68 (m, 2H), 8.03 (d, J=3.0 Hz, 1H). MS (DCI/NH3) m/z=264/266 (M+H)+. Anal. Calcd. for C14H18ClN3.3.15HCl.1.2H2O: C, 42.01; H, 5.93; N, 10.50. Found: C, 42.29; H, 5.56; N, 10.10.

Sources & evidence

ORD record
ord-bef4d375f835442ca414006948de7d91
Source dataset
uspto-grants-2015_03
Patent number
US08987453B2

Reaction notes

Loading…