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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 878741Generated: October 30, 2026

2,4-Difluorophenylacetic acid → HCID 26597804, compound

https://huagongshe.com/reaction/878741

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-Difluorophenylacetic acidHCID 123581—
ReactantPotassium methyl malonateHCID 2724687—
ProductHCID 26597804HCID 26597804—

Reaction Steps

The title compound was prepared from 2-(2,4-difluorophenyl)acetic acid and 3-methoxy-3-oxopropanoic acid potassium salt according to the procedure for the preparation of Example 170, part A. 1H NMR (300 MHz, CDCl3): δ 3.54 (2H, s), 3.76 (3H, s), 3.86 (2H, s), 6.83-6.90 (2H, m), 7.13-7.19 (1H, m).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987461B2
Source datasetuspto-grants-2015_03
ORD IDord-866ba83166284c7d98bb420ec6090898
Source noteuspto-grants-2015_03