HRID878953

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2737573

2-Fluoro-6-(trifluoromethyl)benzyl bromide

C8H5BrF4

HCID54488924

未命名化合物

PRODUCTS

生成物

HCID54488924

未命名化合物

结构：O=C(O)Cc1ccc2ccn(Cc3c(F)cccc3C(F)(F)F)c2c1

HCID68183776

未命名化合物

PROCEDURE

实验过程

The titled compound (16 mg) as a white solid was prepared from the compound [4-6] obtained in the process (6) of Example 4 (100 mg) and 2-fluoro-6-(trifluoromethyl)benzyl bromide according to the method of the process (7) of Example 4.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6261786e14a242bb84de205d3a9042b2
来源数据集: uspto-grants-2015_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08987473B2
来源说明: uspto-grants-2015_03

反应 SMILES

[F:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10]([F:13])([F:12])[F:11])[C:3]=1[CH2:4]Br.[CH2:14]([N:21]1[C:29]2[C:24](=[CH:25][CH:26]=[C:27]([CH2:30][C:31]([OH:33])=[O:32])[CH:28]=2)[CH:23]=[CH:22]1)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[F:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10]([F:13])([F:12])[F:11])[C:3]=1[CH2:4][N:21]1[C:29]2[C:24](=[CH:25][CH:26]=[C:27]([CH2:30][C:31]([OH:33])=[O:32])[CH:28]=2)[CH:23]=[CH:22]1.[CH2:14]([N:21]1[C:29]2[C:24](=[CH:25][CH:26]=[C:27]([CH2:30][C:31]([OH:33])=[O:32])[CH:28]=2)[CH:23]=[CH:22]1)[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1