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2-(Bromomethyl)-1-fluoro-3-(trifluoromethyl)benzene → 2-(1-benzyl-1H-indole-6-yl)acetic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(Bromomethyl)-1-fluoro-3-(trifluoromethyl)benzene | HCID 2737573 | — |
| 反応物 | 2-(1-benzyl-1H-indole-6-yl)acetic acid | HCID 54488924 | — |
| 生成物 | 2-(1-benzyl-1H-indole-6-yl)acetic acid | HCID 54488924 | — |
| 生成物 | 2-{1-[2-fluoro-6-(trifluoromethyl)benzyl]-1H-indole-6-yl}acetic acid | HCID 68183776 | — |
反応手順
The titled compound (16 mg) as a white solid was prepared from the compound [4-6] obtained in the process (6) of Example 4 (100 mg) and 2-fluoro-6-(trifluoromethyl)benzyl bromide according to the method of the process (7) of Example 4.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08987473B2 |
| 出典データセット | uspto-grants-2015_03 |
| ORD ID | ord-6261786e14a242bb84de205d3a9042b2 |
| 出典メモ | uspto-grants-2015_03 |