化工社化工社 化学情報印刷レポート · 研究参考用
1-(Chloromethyl)-2,4-difluorobenzene → 2-(1-benzyl-1H-indole-6-yl)acetic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(Chloromethyl)-2,4-difluorobenzene | HCID 2736948 | — |
| 反応物 | 2-(1-benzyl-1H-indole-6-yl)acetic acid | HCID 54488924 | — |
| 生成物 | 2-(1-benzyl-1H-indole-6-yl)acetic acid | HCID 54488924 | — |
| 生成物 | 2-[1-(2,4-difluorobenzyl)-1H-indole-6-yl]acetic acid | HCID 68184418 | — |
反応手順
The titled compound (35 mg) as a white solid was prepared from the compound [4-6] obtained in the process (6) of Example 4 (100 mg) and 2,4-difluorobenzyl chloride according to the method of the process (7) of Example 4.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08987473B2 |
| 出典データセット | uspto-grants-2015_03 |
| ORD ID | ord-82860b74122344fba895bbcdbb5aa10a |
| 出典メモ | uspto-grants-2015_03 |