N-Methyl-D-glucamine → HCID 131732628, compound

Participants

Reaction Steps

In a representative procedure and according to a preferred embodiment, the BOPTA ligand is solved in water for injection (WFI) containing about 2 equivalents of meglumine, at room temperature, forming a BOPTA-meglumine salt 1:2 solution, with a concentration of about 0.1-0.15 M. Such solution is then eluted through a column containing the Amberlite IRC 748i resin, saturated with Gd(III) ions, at an elution rate of about 1 to 1.5 bed-volume/h. even more preferably, the present process comprises the steps of:

Provenance & Evidence