Dichloromethane → 4-chloro-8-(2,6-difluorophenyl)-2-(methylsulfinyl)pyrido[2,3-d]pyrimidin-7(8H)-one
Reaction equation
[Cl:1][c:2]1[c:3]2[c:4]([n:5][c:6]([S:8][CH3:9])[n:7]1)[n:10](-[c:15]1[c:16]([F:22])[cH:17][cH:18][cH:19][c:20]1[F:21])[c:11](=[O:14])[cH:12][cH:13]2.[Cl:34][CH2:35][Cl:36].[OH:23][O:24][C:25]([c:26]1[cH:27][c:28]([Cl:29])[cH:30][cH:31][cH:32]1)=[O:33]>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][c:6]([S:8]([CH3:9])=[O:23])[n:7]1)[n:10](-[c:15]1[c:16]([F:22])[cH:17][cH:18][cH:19][c:20]1[F:21])[c:11](=[O:14])[cH:12][cH:13]2Participants
4
Sources & evidence
- ORD record
- ord-ed381788a78243f9b32b096c0395f99e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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