HRID880376

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2734325

3-Cyanophenylboronic acid

C7H6BNO2

HCID68013986

未命名化合物

PRODUCTS

生成物

结构：CC(c1ccccc1)n1ncc(-c2ccccc2C#N)c(-c2ccccc2C#N)c1=O

HCID57385631

未命名化合物

收率 7.4%

结构：CC(c1ccccc1)n1ncc(-c2cccc(C#N)c2)c(-c2cccc(C#N)c2)c1=O

HCID57385884

未命名化合物

PROCEDURE

实验过程

Compound 5 is prepared from intermediate 1a and 3-cyanophenylboronic acid under the conditions described for example 4. The minor product formed (solid) corresponds to compound 4 (yield:7.4%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a72171a545f64f79a8acb4dcdd0adc41
来源数据集: uspto-grants-2015_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08993569B2
来源说明: uspto-grants-2015_03

反应 SMILES

Cl[C:2]1[C:3](=[O:17])[N:4]([CH:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH3:10])[N:5]=[CH:6][C:7]=1Cl.[C:18]([C:20]1[CH:21]=[C:22](B(O)O)[CH:23]=[CH:24][CH:25]=1)#[N:19]>>[O:17]=[C:3]1[N:4]([CH:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH3:10])[N:5]=[CH:6][C:7]([C:24]2[CH:25]=[C:20]([CH:21]=[CH:22][CH:23]=2)[C:18]#[N:19])=[C:2]1[C:13]1[CH:12]=[C:11]([CH:16]=[CH:15][CH:14]=1)[C:9]#[N:4].[O:17]=[C:3]1[N:4]([CH:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH3:10])[N:5]=[CH:6][C:7]([C:25]2[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=2[C:18]#[N:19])=[C:2]1[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=1[C:9]#[N:4]