HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4,5-Bis-(4-methoxy-phenyl)-2-(1-phenyl-ethyl)-2H-pyridazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | (4-Methoxyphenyl)boronic acid | HCID 201262 | — |
| Reactant | 4,5-dichloro-2-(1-phenylethyl)pyridazin-3(2H)-one | HCID 68013986 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Solvent | 1,4-Dioxane--water (1/1) | HCID 21886435 | — |
| Product | 4,5-Bis-(4-methoxy-phenyl)-2-(1-phenyl-ethyl)-2H-pyridazin-3-one | HCID 57385635 | — |
Reaction Steps
Compound 6 is prepared from intermediate 1a and 4-methoxyphenylboronic acid under the conditions described for example 1 using tetrakis(triphenylphosphine)palladium(0), K2CO3 and a mixture of dioxane/water: 3/1. Compound 6 is isolated in solid form (yield: 71%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08993569B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-6c91be9b8d7f43b6a23026198536c850 |
| Source note | uspto-grants-2015_03 |