HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 58097333, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 4-Bromo-2-(trifluoromethyl)aniline | HCID 67960 | — |
| Reactant | 3,3-Dimethylbutanoyl chloride | HCID 81514 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 58097333 | HCID 58097333 | 79% |
Reaction Steps
3,3-Dimethylbutanoyl chloride (617 mg, 0.64 mL, 4.6 mmol) was added to a solution of 4-Bromo-2-trifluoromethyl-phenylamine (1.0 g, 4.16 mmol) in acetonitrile (10 mL). The reaction mixture was stirred at room temperature overnight. Water was added to the mixture and the precipitate formed collected to give the title compound as a powder (1.1 g, 79% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08993593B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-4157cdd4508e488996fad131ebe443e6 |
| Source note | uspto-grants-2015_03 |