HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Bromoisoquinolin-3-amine → 3-Aminoisoquinoline-7-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Bromoisoquinolin-3-amine | HCID 52987757 | — |
| Reactant | 7-(trifluoromethyl)-1H-indazole-5-carboxylic acid | HCID 67491810 | — |
| Product | 3-Aminoisoquinoline-7-carboxylic acid | HCID 67491329 | — |
Reaction Steps
The title compound was prepared by a method analogous to that described in Steps 3-4 of Intermediate 21, using 7-bromoisoquinolin-3-amine. +ESI (M+H) 189.2; 1H NMR (400 MHz, CD3OD, δ): 8.87 (s, 1H), 8.52 (d, J=0.78 Hz, 1H), 7.98 (dd, J=8.78, 1.76 Hz, 1H), 7.54 (d, J=8.78 Hz, 1H), 6.77 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08993586B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-40aae240cfb6491aa15a0fc44c1785ff |
| Source note | uspto-grants-2015_03 |