Dichloromethane → 1-(2-Chloro-pyridin-3-yl)-piperazine

HRID 88123Notes

Reaction equation

HRID 88123 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]([Cl:20])[n:16][cH:17][cH:18][cH:19]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:28][CH2:29][Cl:30].[OH:21][C:22]([C:23]([F:24])([F:25])[F:26])=[O:27]>>[NH:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]([Cl:20])[n:16][cH:17][cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 593218363-(4-BOC-piperazino)-2-chloropyridine

Product 1

HCID 592522291-(2-Chloro-pyridin-3-yl)-piperazine

Sources & evidence

ORD record
ord-67a712c9c0be47b2924df1405feadb3d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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