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HRID881243

反应详情

EQUATION

反应方程式

HRID 881243 的结构方程式

REACTANTS

反应物

3
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CC(C)(C)OC(=O)CC(C)(N)C(=O)O
HCID19692748

未命名化合物

结构：Nc1ncc(-c2nc(N3CCOCC3)c3sc(CN4CCNCC4)cc3n2)cn1
HCID58234035

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(N)C(=O)N1CCN(Cc2cc3nc(-c4cnc(N)nc4)nc(N4CCOCC4)c3s2)CC1
HCID58234087

未命名化合物

PROCEDURE

实验过程

The HCl salt of 5-(4-morpholino-6-((piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine (100 mg) was reacted with Boc-2-aminoisobutyric Acid via General Procedure B followed by Boc removal with TFA to generate 28.8 mg of 103 after purification. MS (Q1) 498.3 (M)+.

WORKUP

后处理

  1. customfollowed by Boc removal with TFA
  2. customafter purification