HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-4-(methylamino)piperidine → N-((2-chloro-4-morpholinothieno[2,3-d]pyrimidin-6-yl)methyl)-N,1-dimethylpiperidin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-4-(methylamino)piperidine | HCID 566323 | — |
| Reactant | 2-Chloro-4-morpholinothieno[2,3-d]pyrimidine-6-carbaldehyde | HCID 56833844 | — |
| Product | N-((2-chloro-4-morpholinothieno[2,3-d]pyrimidin-6-yl)methyl)-N,1-dimethylpiperidin-4-amine | HCID 86623517 | — |
Reaction Steps
1-Methyl-4-(methylamino)-piperidine was reacted with 2-chloro-4-morpholinothieno[2,3-d]pyrimidine-6-carbaldehyde via General Procedure B-3. Purification on silica yielded (2-chloro-4-morpholin-4-yl-thieno[2,3-d]pyrimidin-6-ylmethyl)-methyl-(1-methyl-piperidin-4-yl)-amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08993563B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-9b9237af1d61474ab4937c54e66c245f |
| Source note | uspto-grants-2015_03 |