Hydrochloric Acid → 2-N-[4-(2-methylimidazol-1-yl)phenyl]-4-N-(oxolan-2-ylmethyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-2,4-diamine

HRID 88151Notes

Reaction equation

HRID 88151 reaction equation
[CH3:1][c:2]1[n:3](-[c:7]2[cH:8][cH:9][c:10]([NH:13][c:14]3[n:15][c:16]([NH:31][CH2:32][CH:33]4[O:34][CH2:35][CH2:36][CH2:37]4)[c:17]4[c:18]([n:19]3)[CH2:20][CH2:21][N:22]([C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])[CH2:23]4)[cH:11][cH:12]2)[cH:4][cH:5][n:6]1.[CH3:39][OH:40].[ClH:38]>>[CH3:1][c:2]1[n:3](-[c:7]2[cH:8][cH:9][c:10]([NH:13][c:14]3[n:15][c:16]([NH:31][CH2:32][CH:33]4[O:34][CH2:35][CH2:36][CH2:37]4)[c:17]4[c:18]([n:19]3)[CH2:20][CH2:21][NH:22][CH2:23]4)[cH:11][cH:12]2)[cH:4][cH:5][n:6]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 67423223tert-butyl 2-[4-(2-methylimidazol-1-yl)anilino]-4-(oxolan-2-ylmethylamino)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-6-carboxylate

Product 1

HCID 674226212-N-[4-(2-methylimidazol-1-yl)phenyl]-4-N-(oxolan-2-ylmethyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-2,4-diamine

Sources & evidence

ORD record
ord-f5884394bcfd4a0aab9e7e5ecd1b3a1f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…