HRID881519

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID17750212

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine

C10H16BN3O2

结构：OCCN1CCN(Cc2cc3c(N4CCOCC4)nc(Cl)nc3s2)CC1

HCID58233992

未命名化合物

PRODUCTS

生成物

结构：Nc1ncc(-c2nc(N3CCOCC3)c3cc(CN4CCN(CCO)CC4)sc3n2)cn1

HCID58233900

未命名化合物

PROCEDURE

实验过程

2-(4-((2-chloro-4-morpholinothieno[2,3-d]pyrimidin-6-yl)methyl)piperazin-1-yl)ethanol (175 mg) was utilized in a Suzuki coupling with 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine according to General Procedure Suzuki to provide 385 (20 mg) after reverse phase HPLC purification. MS (Q1) 457 (M)+