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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 881596Generated: November 4, 2026

[3-(Benzyloxy)-4-methylphenyl]methanol → 3-(Benzyloxy)-4-methylbenzaldehyde

https://huagongshe.com/reaction/881596

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[3-(Benzyloxy)-4-methylphenyl]methanolHCID 24721056—
CatalystHCID 178418406HCID 178418406—
SolventDichloromethaneHCID 6344—
Product3-(Benzyloxy)-4-methylbenzaldehydeHCID 1610138939.3%

Reaction Steps

To a solution of (3-benzyloxy-4-methylphenyl)methanol (1.0 g) in dichloromethane (50 mL) was added manganese dioxide (2.5 g), and this mixture was stirred at room temperature for 2 days. The insoluble material was removed by filtration and this filtrate was concentrated under reduced pressure. This residue was purified by column chromatography on silica gel (eluent: n-hexane/ethyl acetate) to give the title compound (0.39 g)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08993616B2
Source datasetuspto-grants-2015_03
ORD IDord-6f0715ca5d994056bedf93c762e7f939
Source noteuspto-grants-2015_03