Hydrochloric Acid → HCID 68753672, compound

Participants

Reaction Steps

Next, to a solution of (S)-4-tert-butoxycarbonylamino-5-(2′-methoxy-biphenyl-4-yl)-2-methyl-pentanoic acid ethyl ester (473 mg, 1.017 mmol) in DCM (5 ml) was added HCl in dioxane (4M, 1 ml), and the resulting mixture was stirred at room temperature for 2 hours. Then, the mixture was concentrated on under reduced pressure. The obtained residue was used for next step without further purification. HPLC Retention time 1.28 minutes (condition A): MS 342.4 (M+1).

Provenance & Evidence