Methanol → 1-{4-[1-(4-Amino-3-methoxyphenyl)piperidin-4-yl]piperazin-1-yl}ethan-1-one
Reaction equation
[BH4-:1].[C:3]([CH3:4])(=[O:5])[N:6]1[CH2:7][CH2:8][N:9]([CH:12]2[CH2:13][CH2:14][N:15]([c:18]3[cH:19][c:20]([O:27][CH3:28])[c:21]([N+:24]([O-:25])=[O:26])[cH:22][cH:23]3)[CH2:16][CH2:17]2)[CH2:10][CH2:11]1.[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:29][OH:30].[Na+:2].[Ni:37]([Cl:38])[Cl:39].[OH2:31].[OH2:32].[OH2:33].[OH2:34].[OH2:35].[OH2:36]>>[C:3]([CH3:4])(=[O:5])[N:6]1[CH2:7][CH2:8][N:9]([CH:12]2[CH2:13][CH2:14][N:15]([c:18]3[cH:19][c:20]([O:27][CH3:28])[c:21]([NH2:24])[cH:22][cH:23]3)[CH2:16][CH2:17]2)[CH2:10][CH2:11]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-543792b43da7488e9bbfc40a14394eed
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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