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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 882580Generated: October 26, 2026

Trifluoroacetic acid → Ethyl-(1S,2R)-1-amino-2-phenylcyclopropanecarboxylate trifluoroacetate

https://huagongshe.com/reaction/882580

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant(1S,2R)-N-Boc-1-amino-2-phenylcyclopropanecarboxylic acidHCID 7009512—
SolventEthanolHCID 702—
ProductEthyl-(1S,2R)-1-amino-2-phenylcyclopropanecarboxylate trifluoroacetateHCID 86678341—

Reaction Steps

The title compound was prepared by standard methods, by esterifying commercially available (1S,2R)-1-[(tert-butoxycarbonyl)amino]-2-phenylcyclopropanecarboxylic acid with ethanol and subsequent Boc detachment with trifluoroacetic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08992932B2
Source datasetuspto-grants-2015_03
ORD IDord-c93405c8754e4f1882819b8547f69384
Source noteuspto-grants-2015_03